According to the World Health Organization, more than one-third of the world’s population – 2 billion people – are infected with tuberculosis, including an estimated 10-15 million residing in the U.S. TB is typically a latent infection, meaning those infected are carriers, but asymptomatic and non-contagious. However, carriers can develop active TB at any time. Each year, 5-10% of the infected population develops active TB disease, usually due to immunosuppressive circumstances. In 2013 alone, 9 million people fell ill from and 1.5 million deaths were attributed to active TB disease.

Current tuberculosis tests are prone to false positives.